human CHRNA5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CHRNA5.
shAAV-205214
AAV-h-CHRNA5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CHRNA5 (cholinergic receptor nicotinic alpha 5 subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LNCR2
Description (Vector)
CHRNA5 is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).
Gene ID
1138
Gene Name (Vector)
cholinergic receptor nicotinic alpha 5 subunit
Gene Symbol
CHRNA5
HGNC ID
HGNC:1959
ORF Size (aa)
1407
ORF Size (bp)
1407 bp
RefSeq ID
NM_000745
RefSeq Synonyms
NM_001307945, NM_000745, BC033639,
Species
human
UniGene ID
Hs.625152
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.