human CES2 shRNA silencing AAV

Name 
AAV-h-CES2-shRNA
Cat No 
shAAV-205021
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CES2.

shAAV-205021
AAV-h-CES2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CES2 (carboxylesterase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CE-2; CES2A1; iCE; PCE-2
Description (Vector)
CES2 encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.
Gene ID
8824
Gene Name (Vector)
carboxylesterase 2
Gene Symbol
CES2
HGNC ID
HGNC:1864
ORF Size (aa)
1872
ORF Size (bp)
1872 bp
RefSeq ID
NM_003869
RefSeq Synonyms
NM_198061, NM_003869, BC032095,
Species
human
UniGene ID
Hs.282975

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.