human CENPL shRNA silencing AAV

Name
AAV-h-CENPL-shRNA

Cat No
shAAV-204966

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CENPL.

shAAV-204966

AAV-h-CENPL-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CENPL (centromere protein L). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C1orf155; CENP-L; dJ383J4.3

Description (Vector)

CENPL is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006) (PubMed 16622420).(supplied by OMIM, Mar 2008)

Gene ID

91687

Gene Name (Vector)

centromere protein L

Gene Symbol

CENPL

HGNC ID

HGNC:17879

ORF Size (aa)

1035

ORF Size (bp)

1035 bp

RefSeq ID

NM_033319

RefSeq Synonyms

NM_033319, NM_001171182, NM_001127181, BC066658, BC033154, BC007071,

Species

human

UniGene ID

Hs.531856

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.