human CEBPA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CEBPA.
shAAV-204935
AAV-h-CEBPA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CEBPA (CCAAT/enhancer binding protein alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C/EBP-alpha; CEBP
Description (Vector)
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Gene ID
1050
Gene Name (Vector)
CCAAT/enhancer binding protein alpha
Gene Symbol
CEBPA
HGNC ID
HGNC:1833
ORF Size (aa)
1077
RefSeq ID
NM_004364
RefSeq Synonyms
NM_004364, NM_001287435, NM_001287424, NM_001285829, BC160133,
Species
human
UniGene ID
Hs.699463
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.