human CEACAM3 shRNA silencing AAV

Cat. No: shAAV-204929

Availability: 6-8 weeks

Name: AAV-h-CEACAM3-shRNA

This is an AAV expressing shRNA for silencing of Human CEACAM3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CEACAM3
Gene Name: carcinoembryonic antigen related cell adhesion molecule 3
Gene ID: 1084
Gene Synonyms: CD66D; CEA; CGM1; W264; W282
ORF Size: 759 bp
RefSeq#: NM_001815
Gene Description: CEACAM3 encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
UniGene ID: Hs.11
HGNC ID: HGNC:1815