human CDKN3 shRNA silencing AAV

Name 
AAV-h-CDKN3-shRNA
Cat No 
shAAV-204888
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CDKN3.

shAAV-204888
AAV-h-CDKN3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CDKN3 (cyclin dependent kinase inhibitor 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CDI1; CIP2; KAP; KAP1
Description (Vector)
CDKN3 belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
1033
Gene Name (Vector)
cyclin dependent kinase inhibitor 3
Gene Symbol
CDKN3
HGNC ID
HGNC:1791
ORF Size (aa)
519
ORF Size (bp)
519 bp
RefSeq ID
NM_005192
RefSeq Synonyms
NM_005192, NM_001330173, NM_001130851, BC064965,
Species
human
UniGene ID
Hs.84113

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.