human CDH7 shRNA silencing AAV

Name
AAV-h-CDH7-shRNA

Cat No
shAAV-204832

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CDH7.

shAAV-204832

AAV-h-CDH7-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CDH7 (cadherin 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CDH7L1

Description (Vector)

CDH7 is a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures. Alternative splicing in the 5' UTR of this gene yields variant transcripts encoding the same protein.

Gene ID

1005

Gene Name (Vector)

cadherin 7

Gene Symbol

CDH7

HGNC ID

HGNC:1766

ORF Size (aa)

1893

ORF Size (bp)

1893 bp

RefSeq ID

NM_004361

RefSeq Synonyms

NM_033646, NM_004361, NM_001317214, BC036786,

Species

human

UniGene ID

Hs.657522

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.