human CDH12 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CDH12.
shAAV-204805
AAV-h-CDH12-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CDH12 (cadherin 12). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CDHB
Description (Vector)
CDH12 encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
Gene ID
1010
Gene Name (Vector)
cadherin 12
Gene Symbol
CDH12
HGNC ID
HGNC:1751
ORF Size (aa)
2385
ORF Size (bp)
2385 bp
RefSeq ID
NM_004061
RefSeq Synonyms
NM_004061, NM_001317228, NM_001317227, BC047608,
Species
human
UniGene ID
Hs.113684
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.