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human CDH11 shRNA silencing AAV

Name 
AAV-h-CDH11-shRNA
Cat No 
shAAV-204804
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CDH11.

shAAV-204804
AAV-h-CDH11-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CDH11 (cadherin 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CAD11; CDHOB; OB; OSF-4
Description (Vector)
CDH11 encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
Gene ID
1009
Gene Name (Vector)
cadherin 11
Gene Symbol
CDH11
HGNC ID
HGNC:1750
ORF Size (aa)
2391
ORF Size (bp)
2391 bp
RefSeq ID
NM_001797
RefSeq Synonyms
NM_001797, NM_001330576, NM_001308392, BC013609,
Species
human
UniGene ID
Hs.116471

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.