human CDCA4 shRNA silencing AAV

Name
AAV-h-CDCA4-shRNA

Cat No
shAAV-204787

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CDCA4.

shAAV-204787

AAV-h-CDCA4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CDCA4 (cell division cycle associated 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HEPP; SEI-3/HEPP

Description (Vector)

CDCA4 encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulaton of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1.

Gene ID

55038

Gene Name (Vector)

cell division cycle associated 4

Gene Symbol

CDCA4

HGNC ID

HGNC:14625

ORF Size (aa)

726

ORF Size (bp)

726 bp

RefSeq ID

NM_145701

RefSeq Synonyms

NM_145701, NM_017955, BC025263, BC011736,

Species

human

UniGene ID

Hs.715701

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.