human CDC5L shRNA silencing AAV

Name
AAV-h-CDC5L-shRNA

Cat No
shAAV-204778

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CDC5L.

shAAV-204778

AAV-h-CDC5L-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CDC5L (cell division cycle 5 like). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CDC5; CDC5 cell division cycle 5-like; CDC5-LIKE; Cdc5-like protein; Cdc5-related protein; CEF1; cell division cycle 5-like protein; dJ319D22.1; dJ319D22.1 (CDC5-like protein); PCDC5RP; pombe cdc5-related protein

Description (eCommerce)

CDC5L (cell division cycle 5-like protein) has been identified as a component of the human splicesome and is important to pre-mRNA splicing as well as cell cycle progression.

Description (Vector)

CDC5L shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.

Gene ID

988

Gene Name (eCommerce)

cell division cycle 5 like

Gene Name (Vector)

cell division cycle 5 like

Gene Symbol

CDC5L

HGNC ID

HGNC:1743

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2409

ORF Size (bp)

2409 bp

Protein Name (eCommerce)

Cell division cycle 5-like protein

RefSeq ID

NM_001253

RefSeq Synonyms

NM_001253, BC001568,

Research Areas

Cell Cycle,Gene Expression,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing,Spliceosome,Transcription Factor/Regulator

Research Areas (Faceted)

cell_biology,cell_cycle,genetics,transcription_translation

Species

human

Target Sentence

CDC5L (cell division cycle 5-like protein) has been identified as a component of the human splicesome and is important to pre-mRNA splicing as well as cell cycle progression.

UniGene ID

Hs.485471

UniProt ID (eCommerce)

Q99459

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.