human CD63 shRNA silencing AAV

Name
AAV-h-CD63-shRNA

Cat No
shAAV-204672

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CD63.

shAAV-204672

AAV-h-CD63-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CD63 (CD63 molecule). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

LAMP-3; ME491; MLA1; OMA81H; TSPAN30

Description (Vector)

CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.

Gene ID

967

Gene Name (Vector)

CD63 molecule

Gene Symbol

CD63

HGNC ID

HGNC:1692

ORF Size (aa)

717

ORF Size (bp)

717 bp

RefSeq ID

NM_001780

RefSeq Synonyms

NM_001780, NM_001267698, NM_001257401, NM_001257400, NM_001257392, NM_001257391, NM_001257390, NM_001257389, NM_001040034, BC013017, BC002349,

Species

human

UniGene ID

Hs.445570

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.