human CD63 shRNA silencing AAV

Cat. No: shAAV-204672

Availability: 4-5 weeks

Name: AAV-h-CD63-shRNA

This is an AAV expressing shRNA for silencing of Human CD63.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CD63
Gene Name: CD63 molecule
Gene ID: 967
Gene Synonyms: LAMP-3; ME491; MLA1; OMA81H; TSPAN30
ORF Size: 717 bp
RefSeq#: NM_001780
Gene Description: CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.
UniGene ID: Hs.445570
HGNC ID: HGNC:1692