human CD44 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CD44.
shAAV-204656
AAV-h-CD44-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CD44 (CD44 molecule (Indian blood group)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD antigen CD44; CD44 antigen; CDW44; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; ECMR-III; epican; extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HCELL; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; Hermes antigen; homing function and Indian blood group system; HUTCH-I; hyaluronate receptor; IN; Indian blood group antigen; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; PGP-1; PGP-I; phagocytic glycoprotein 1; Phagocytic glycoprotein I; soluble CD44
Description (eCommerce)
CD44 is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis [taken from NCBI Entrez Gene (Gene ID: 960)].
Description (Vector)
CD44 is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
Gene ID
960
Gene Name (eCommerce)
CD44 molecule (Indian blood group)
Gene Name (Vector)
CD44 molecule (Indian blood group)
Gene Symbol
CD44
HGNC ID
HGNC:1681
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2100
ORF Size (bp)
2100 bp
Protein Name (eCommerce)
CD44 antigen
RefSeq ID
NM_000610
RefSeq Synonyms
NM_001202557, NM_001202556, NM_001202555, NM_001001392, NM_001001391, NM_001001390, NM_001001389, NM_000610, BC004372,
Research Areas
Apoptosis,Autophagy,Cancer,DNA Damage/Repair,FGF Signaling,Gene Expression,Host-Virus Interactions,IFN Signaling,Immunology,Metabolism/Metabolic Process,MicroRNAs in Cancer,Signal Transduction,TGF-beta Signaling,Wnt Signaling
Research Areas (Faceted)
cancer,cell_biology,genetics,immunology,infectious_disease,metabolism,signal_transduction,transcription_translation
Species
human
Target Sentence
CD44 is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis [taken from NCBI Entrez Gene (Gene ID: 960)].
UniGene ID
Hs.502328
UniProt ID (eCommerce)
P16070
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.