human CBY1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CBY1.
shAAV-204207
AAV-h-CBY1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CBY1 (chibby family member 1, beta catenin antagonist). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
arb1; C22orf2; CBY; HS508I15A; PGEA1; PIGEA-14; PIGEA14
Description (Vector)
Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
25776
Gene Name (Vector)
chibby family member 1, beta catenin antagonist
Gene Symbol
CBY1
HGNC ID
HGNC:1307
ORF Size (aa)
381
ORF Size (bp)
381 bp
RefSeq ID
NM_001002880
RefSeq Synonyms
NM_015373, NM_001002880, BC016139,
Species
human
UniGene ID
Hs.596584
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.