human CABLES1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CABLES1.
shAAV-203892
AAV-h-CABLES1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CABLES1 (Cdk5 and Abl enzyme substrate 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CABL1; CABLES; HsT2563; IK3-1
Description (Vector)
CABLES1 encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
91768
Gene Name (Vector)
Cdk5 and Abl enzyme substrate 1
Gene Symbol
CABLES1
HGNC ID
HGNC:25097
ORF Size (aa)
1107
ORF Size (bp)
1107 bp
RefSeq ID
NM_138375
RefSeq Synonyms
NM_138375, NM_001256438, NM_001100619, BC037218,
Species
human
UniGene ID
Hs.11108
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.