human CA8 shRNA silencing AAV

Name 
AAV-h-CA8-shRNA
Cat No 
shAAV-203883
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CA8.

shAAV-203883
AAV-h-CA8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CA8 (carbonic anhydrase 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CA-RP; CA-VIII; CALS; CAMRQ3; CARP
Description (Vector)
CA8 was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form.
Gene ID
767
Gene Name (Vector)
carbonic anhydrase 8
Gene Symbol
CA8
HGNC ID
HGNC:1382
ORF Size (aa)
873
ORF Size (bp)
873 bp
RefSeq ID
NM_004056
RefSeq Synonyms
NM_004056, NM_001321839, NM_001321838, NM_001321837, BC108929, BC069794, BC069744, BC015531,
Species
human
UniGene ID
Hs.654388

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.