human C9ORF31 shRNA silencing AAV

Name 
AAV-h-C9ORF31-shRNA
Cat No 
shAAV-203815
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GSN.

shAAV-203815
AAV-h-C9ORF31-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GSN (gelsolin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ADF; AGEL
Description (Vector)
GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
Gene ID
2934
Gene Name (Vector)
gelsolin
Gene Symbol
GSN
HGNC ID
HGNC:4620
ORF Size (aa)
2349
ORF Size (bp)
2349 bp
RefSeq ID
NM_000177
RefSeq Synonyms
NM_198252, NM_001258030, NM_001258029, NM_001127667, NM_001127666, NM_001127665, NM_001127664, NM_001127663, NM_001127662, NM_000177, BC026033,
Species
human
UniGene ID
Hs.522373

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.