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human C8B shRNA silencing AAV

Name 
AAV-h-C8B-shRNA
Cat No 
shAAV-203713
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human C8B.

shAAV-203713
AAV-h-C8B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human C8B (complement C8 beta chain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C82
Description (Vector)
C8 beta is one of the three subunits that comprise the component 8 (C8) of the complement system. C8 participates in the formation of Membrane Attack Complex that results in the lysis of cells. Patients with C8B deficiency are prone to bacteria infection.
Gene ID
732
Gene Name (Vector)
complement C8 beta chain
Gene Symbol
C8B
HGNC ID
HGNC:1353
ORF Size (aa)
1776
ORF Size (bp)
1776 bp
RefSeq ID
NM_000066
RefSeq Synonyms
NM_001278544, NM_001278543, NM_000066, BC130575,
Species
human
UniGene ID
Hs.391835

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.