human C7ORF16 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PPP1R17.
shAAV-203646
AAV-h-C7ORF16-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PPP1R17 (protein phosphatase 1 regulatory subunit 17). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C7orf16; GSBS
Description (Vector)
PPP1R17 is found primarily in cerebellar Purkinje cells, where it functions as a protein phosphatase inhibitor. The encoded protein is a substrate for cGMP-dependent protein kinase. An allele of this gene was discovered that increases susceptibility to hypercholesterolemia. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
10842
Gene Name (Vector)
protein phosphatase 1 regulatory subunit 17
Gene Symbol
PPP1R17
HGNC ID
HGNC:16973
ORF Size (aa)
468
RefSeq ID
NM_006658
RefSeq Synonyms
NM_006658, NM_001145123, BC028094,
Species
human
UniGene ID
Hs.227011
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.