human C2ORF37 shRNA silencing AAV

Name
AAV-h-C2ORF37-shRNA

Cat No
shAAV-203302

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human DCAF17.

shAAV-203302

AAV-h-C2ORF37-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DCAF17 (DDB1 and CUL4 associated factor 17). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C2orf37

Description (Vector)

DCAF17 encodes a nuclear transmembrane protein that associates with cullin 4A/damaged DNA binding protein 1 ubiquitin ligase complex. Mutations in this gene are associated with Woodhouse-Sakati syndrome. Alternate splicing results in multiple transcript variants.

Gene ID

80067

Gene Name (Vector)

DDB1 and CUL4 associated factor 17

Gene Symbol

DCAF17

HGNC ID

HGNC:25784

ORF Size (aa)

1563

ORF Size (bp)

1563 bp

RefSeq ID

NM_025000

RefSeq Synonyms

NM_025000, NM_001164821, BC140843,

Species

human

UniGene ID

Hs.659439

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.