human C14ORF169 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human C14orf169.
shAAV-202653
AAV-h-C14ORF169-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human C14orf169 (chromosome 14 open reading frame 169). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
60S ribosomal protein L8 histidine hydroxylase; bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; C14orf169; histone lysine demethylase NO66; hsNO66; JMJD9; lysine-specific demethylase NO66; MAPJD; MYC-associated protein with JmjC domain; NO66; nucleolar protein 66; ribosomal oxygenase 1; ribosomal oxygenase NO66; ROX; up-regulated in lung cancer 2; URLC2
Description (eCommerce)
lysine-specific demethylase NO66 (nucleolar protein 66) specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Additionally, NO66, preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2).
Gene ID
79697
Gene Name (eCommerce)
ribosomal oxygenase 1
Gene Name (Vector)
chromosome 14 open reading frame 169
Gene Symbol
C14orf169
HGNC ID
HGNC:20968
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1926
ORF Size (bp)
1926 bp
Protein Name (eCommerce)
Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66
RefSeq ID
NM_024644
RefSeq Synonyms
NM_024644, BC071954, BC011350,
Research Areas
Cancer,Cell Biology,Chromatin Remodeling,Histone Modification,Transcription Factor/Regulator
Research Areas (Faceted)
cancer,cell_biology,genetics,transcription_translation
Species
human
Target Sentence
lysine-specific demethylase NO66 (nucleolar protein 66) specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Additionally, NO66, preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2).
UniGene ID
Hs.509916
UniProt ID (eCommerce)
Q9H6W3
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.