human C14ORF147 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SPTSSA.
shAAV-202640
AAV-h-C14ORF147-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SPTSSA (serine palmitoyltransferase small subunit A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C14orf147; SSSPTA
Description (Vector)
Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTA is a small SPT subunit that stimulates SPT activity and confers acyl-CoA preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM 611120) (Han et al., 2009 (PubMed 19416851)).(supplied by OMIM, Nov 2010)
Gene ID
171546
Gene Name (Vector)
serine palmitoyltransferase small subunit A
Gene Symbol
SPTSSA
HGNC ID
HGNC:20361
ORF Size (aa)
207
RefSeq ID
NM_138288
RefSeq Synonyms
NM_138288, BC068480, BC021701, BC016808, BC016805,
Species
human
UniGene ID
Hs.269909
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.