human BRP44L shRNA silencing AAV

Name 
AAV-h-BRP44L-shRNA
Cat No 
shAAV-202277
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MPC1.

shAAV-202277
AAV-h-BRP44L-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MPC1 (mitochondrial pyruvate carrier 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BRP44L; CGI-129; dJ68L15.3; MPYCD
Description (Vector)
MPC1 is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. The encoded protein is found in the inner mitochondrial membrane. Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency. Several transcript variants, some protein coding and one non-protein coding, have been found for this gene.
Gene ID
51660
Gene Name (Vector)
mitochondrial pyruvate carrier 1
Gene Symbol
MPC1
HGNC ID
HGNC:21606
ORF Size (aa)
330
RefSeq ID
NM_016098
RefSeq Synonyms
NM_016098, NM_001270879, BC000810,
Species
human
UniGene ID
Hs.172755

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.