human BFSP2 shRNA silencing AAV

Cat. No: shAAV-202118

Availability: 6-8 weeks

Name: AAV-h-BFSP2-shRNA

This is an AAV expressing shRNA for silencing of Human BFSP2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BFSP2
Gene Name: beaded filament structural protein 2
Gene ID: 8419
Gene Synonyms: CP47; CP49; CTRCT12; LIFL-L; PHAKOSIN
ORF Size: 1248 bp
RefSeq#: NM_003571
Gene Description: More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.
UniGene ID: Hs.659862
HGNC ID: HGNC:1041