human BCL9L shRNA silencing AAV

Name
AAV-h-BCL9L-shRNA

Cat No
shAAV-202066

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human BCL9L.

shAAV-202066

AAV-h-BCL9L-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BCL9L (B-cell CLL/lymphoma 9-like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

87

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

B-cell CLL/lymphoma 9-like protein; B-cell lymphoma 9-like protein; BCL9-2; BCL9-like protein; DLNB11; nuclear co-factor of beta-catenin signalling; protein BCL9-2

Description (eCommerce)

B-cell lymphoma 9-like protein (BCL9L) is a transcriptional regulator that acts as an activator. BCL9L promotes beta-catenin transcriptional activity and plays a role in tumorigenesis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q86UU0].

Gene ID

283149

Gene Name (eCommerce)

B cell CLL/lymphoma 9 like

Gene Name (Vector)

B-cell CLL/lymphoma 9-like

Gene Symbol

BCL9L

HGNC ID

HGNC:23688

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

4497

ORF Size (bp)

4497 bp

Protein Name (eCommerce)

B-cell CLL/lymphoma 9-like protein

RefSeq ID

NM_182557

RefSeq Synonyms

NM_182557, BC156197,

Research Areas

Signal Transduction,Transcription Factor/Regulator,Wnt Signaling

Research Areas (Faceted)

cell_biology,signal_transduction,transcription_translation

Species

human

Target Sentence

B-cell lymphoma 9-like protein (BCL9L) is a transcriptional regulator that acts as an activator. BCL9L promotes beta-catenin transcriptional activity and plays a role in tumorigenesis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q86UU0].

UniGene ID

Hs.414740

UniProt ID (eCommerce)

Q86UU0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.