human BCHE shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human BCHE.
shAAV-202025
AAV-h-BCHE-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human BCHE (butyrylcholinesterase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CHE1; CHE2; E1
Description (Vector)
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
Gene ID
590
Gene Name (Vector)
butyrylcholinesterase
Gene Symbol
BCHE
HGNC ID
HGNC:983
ORF Size (aa)
1809
ORF Size (bp)
1809 bp
RefSeq ID
NM_000055
RefSeq Synonyms
NM_000055, BC018141, BC008396,
Species
human
UniGene ID
Hs.420483
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.