human BBS12 shRNA silencing AAV

Name 
AAV-h-BBS12-shRNA
Cat No 
shAAV-201997
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human BBS12.

shAAV-201997
AAV-h-BBS12-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BBS12 (Bardet-Biedl syndrome 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C4orf24
Description (Vector)
BBS12 is part of a complex that is involved in membrane trafficking. The encoded protein is a molecular chaperone that aids in protein folding upon ATP hydrolysis. This protein also plays a role in adipocyte differentiation. Defects in this gene are a cause of Bardet-Biedl syndrome type 12. Two transcript variants encoding the same protein have been found for this gene.
Gene ID
166379
Gene Name (Vector)
Bardet-Biedl syndrome 12
Gene Symbol
BBS12
HGNC ID
HGNC:26648
ORF Size (aa)
2133
ORF Size (bp)
2133 bp
RefSeq ID
NM_152618
RefSeq Synonyms
NM_152618, NM_001178007, BC055426,
Species
human
UniGene ID
Hs.400698

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.