human BAZ1B shRNA silencing AAV

Name
AAV-h-BAZ1B-shRNA

Cat No
shAAV-201988

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human BAZ1B.

shAAV-201988

AAV-h-BAZ1B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BAZ1B (bromodomain adjacent to zinc finger domain 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Bromodomain adjacent to zinc finger domain protein 1B; hWALp2; transcription factor WSTF; tyrosine-protein kinase BAZ1B; WBSCR10; WBSCR9; williams syndrome transcription factor; williams-Beuren syndrome chromosomal region 10 protein; williams-Beuren syndrome chromosomal region 9 protein; WSTF

Description (eCommerce)

Williams Syndrome transcription factor (WSTF) gene is one of multiple genes deleted in Williams-Beuren syndrome (WS). WSTF associates with the ISWI-type ATPase SNF2H to form the WICH complex. This complex remodels chromatin at replication foci by mobilizing nucleosomes to allow access of factors to newly replicated DNA for restoration of the epigenetic state.

Description (Vector)

BAZ1B encodes a member of the bromodomain protein family. The bromodomain is a structural motif characteristic of proteins involved in chromatin-dependent regulation of transcription. BAZ1B is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23.

Gene ID

9031

Gene Name (eCommerce)

bromodomain adjacent to zinc finger domain 1B

Gene Name (Vector)

bromodomain adjacent to zinc finger domain 1B

Gene Symbol

BAZ1B

HGNC ID

HGNC:961

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

4452

ORF Size (bp)

4452 bp

Protein Name (eCommerce)

Tyrosine-protein kinase BAZ1B

RefSeq ID

NM_032408

RefSeq Synonyms

NM_032408, BC136520,

Research Areas

Cardiac Development,Cardiology,Cardiovascular,Cell Cycle,Chromatin Remodeling,DNA Damage/Repair,DNA Replication,Gene Expression,Histone Modification,Neurobiology,Replication,Transcription Factor/Regulator,Zinc-finger

Research Areas (Faceted)

cardiovascular,cell_biology,cell_cycle,developmental_biology,genetics,neurobiology,transcription_translation

Species

human

Target Sentence

UniGene ID

Hs.647016

UniProt ID (eCommerce)

Q9UIG0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.