human AZIN1 shRNA silencing AAV

Name
AAV-h-AZIN1-shRNA

Cat No
shAAV-201863

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human AZIN1.

shAAV-201863

AAV-h-AZIN1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AZIN1 (antizyme inhibitor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AZI; AZIA1; OAZI; OAZIN; ODC1L

Description (Vector)

Ornithine decarboxylase (ODC) catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. Ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein encoded by this gene is highly similar to ODC. It binds to ODC antizyme and stabilizes ODC, thus inhibiting antizyme-mediated ODC degradation. Two alternatively spliced transcript variants have been found for this gene.

Gene ID

51582

Gene Name (Vector)

antizyme inhibitor 1

Gene Symbol

AZIN1

HGNC ID

HGNC:16432

ORF Size (aa)

1347

ORF Size (bp)

1347 bp

RefSeq ID

NM_015878

RefSeq Synonyms

NM_148174, NM_015878, NM_001301668, BC019279, BC013420,

Species

human

UniGene ID

Hs.459106

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.