human AZI1 shRNA silencing AAV

Name 
AAV-h-AZI1-shRNA
Cat No 
shAAV-201861
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CEP131.

shAAV-201861
AAV-h-AZI1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CEP131 (centrosomal protein 131). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5-azacytidine induced 1; 5-azacytidine-induced protein 1; AZ1; AZI1; centrosomal protein 131 kDa; centrosomal protein 131kDa; centrosomal protein of 131 kDa; pre-acrosome localization protein 1; ZA1
Description (eCommerce)
CEP131/AZ1 was originally identified as a transcript that was increased in cells exposed to the demethylating agent, azacytidine. It was found to localize to the pre-acrosome region of spermatids and therefore thought to play a role in spermatogenesis. CEP131/AZ1 has also been identified as a component of the centrosome.
Gene ID
22994
Gene Name (eCommerce)
centrosomal protein 131
Gene Name (Vector)
centrosomal protein 131
Gene Symbol
CEP131
HGNC ID
HGNC:29511
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3243
ORF Size (bp)
3243 bp
Protein Name (eCommerce)
Centrosomal protein of 131 kDa
RefSeq ID
NM_014984
RefSeq Synonyms
NM_014984, NM_001319229, NM_001319228, NM_001009811, BC136580, BC136578,
Research Areas
Cell Cycle,Cytoskeleton,Signal Transduction,Spermatogenesis
Research Areas (Faceted)
cell_biology,cell_cycle,developmental_biology,genetics,signal_transduction
Species
human
Target Sentence
CEP131/AZ1 was originally identified as a transcript that was increased in cells exposed to the demethylating agent, azacytidine. It was found to localize to the pre-acrosome region of spermatids and therefore thought to play a role in spermatogenesis. CEP131/AZ1 has also been identified as a component of the centrosome.
UniGene ID
Hs.514578
UniProt ID (eCommerce)
Q9UPN4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.