human ATP5D shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ATP5D.
shAAV-201713
AAV-h-ATP5D-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ATP5D (ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
ATP5D encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). ATP5D encodes the delta subunit of the catalytic core. Alternatively spliced transcript variants encoding the same isoform have been identified.
Gene ID
513
Gene Name (Vector)
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
Gene Symbol
ATP5D
HGNC ID
HGNC:837
ORF Size (aa)
507
ORF Size (bp)
507 bp
RefSeq ID
NM_001687
RefSeq Synonyms
NM_001687, NM_001001975, BC018079, BC004426, BC002389,
Species
human
UniGene ID
Hs.418668
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.