human ATP5B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ATP5B.
shAAV-201707
AAV-h-ATP5B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ATP5B (ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ATPMB; ATPSB; HEL-S-271
Description (Vector)
ATP5B encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). ATP5B encodes the beta subunit of the catalytic core.
Gene ID
506
Gene Name (Vector)
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
Gene Symbol
ATP5B
HGNC ID
HGNC:830
ORF Size (aa)
1590
ORF Size (bp)
1590 bp
RefSeq ID
NM_001686
RefSeq Synonyms
NM_001686, BC016512,
Species
human
UniGene ID
Hs.406510
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.