human ATP2A3 shRNA silencing AAV

Name 
AAV-h-ATP2A3-shRNA
Cat No 
shAAV-201693
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ATP2A3.

shAAV-201693
AAV-h-ATP2A3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ATP2A3 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SERCA3
Description (Vector)
ATP2A3 encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
489
Gene Name (Vector)
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
Gene Symbol
ATP2A3
HGNC ID
HGNC:813
ORF Size (aa)
3000
ORF Size (bp)
3000 bp
RefSeq ID
NM_005173
RefSeq Synonyms
NM_174958, NM_174957, NM_174956, NM_174955, NM_174954, NM_174953, NM_005173, BC035729,
Species
human
UniGene ID
Hs.513870

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.