human ATP12A shRNA silencing AAV

Name
AAV-h-ATP12A-shRNA

Cat No
shAAV-201672

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ATP12A.

shAAV-201672

AAV-h-ATP12A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ATP12A (ATPase H+/K+ transporting non-gastric alpha2 subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

#945; ATP1AL1; HK

Description (Vector)

ATP12A belongs to the family of P-type cation transport ATPases. This gene encodes a catalytic subunit of the ouabain-sensitive H+/K+ -ATPase that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for potassium absorption in various tissues. Two transcript variants encoding different isoforms have been found for this gene.

Gene ID

479

Gene Name (Vector)

ATPase H+/K+ transporting non-gastric alpha2 subunit

Gene Symbol

ATP12A

HGNC ID

HGNC:13816

ORF Size (aa)

3138

ORF Size (bp)

3138 bp

RefSeq ID

NM_001676

RefSeq Synonyms

NM_001676, NM_001185085, BC031609,

Species

human

UniGene ID

Hs.147111

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.