human ATG3 shRNA silencing AAV

Name 
AAV-h-ATG3-shRNA
Cat No 
shAAV-201637
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ATG3.

shAAV-201637
AAV-h-ATG3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ATG3 (autophagy related 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
APG3; APG3-LIKE; APG3L; PC3-96
Description (Vector)
Autophagy is a process of bulk degradation of cytoplasmic components by the lysosome or vacuole. Human ATG3 displays the same enzymatic characteristics in vitro as yeast Apg3, a protein-conjugating enzyme essential for autophagy (Tanida et al., 2002 (PubMed 11825910)).(supplied by OMIM, Mar 2008)
Gene ID
64422
Gene Name (Vector)
autophagy related 3
Gene Symbol
ATG3
HGNC ID
HGNC:20962
ORF Size (aa)
945
ORF Size (bp)
945 bp
RefSeq ID
NM_022488
RefSeq Synonyms
NM_022488, NM_001278712, BC024221, BC002830,
Species
human
UniGene ID
Hs.477126

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.