human ATF3 shRNA silencing AAV

Name
AAV-h-ATF3-shRNA

Cat No
shAAV-201617

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ATF3.

shAAV-201617

AAV-h-ATF3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ATF3 (activating transcription factor 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

ATF3 encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. ATF3 is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes.

Gene ID

467

Gene Name (Vector)

activating transcription factor 3

Gene Symbol

ATF3

HGNC ID

HGNC:785

ORF Size (aa)

546

ORF Size (bp)

546 bp

RefSeq ID

NM_001674

RefSeq Synonyms

NM_001674, NM_001206488, NM_001206486, NM_001206485, NM_001206484, NM_001040619, NM_001030287, BC006322,

Species

human

UniGene ID

Hs.460

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.