human ATAD5 shRNA silencing AAV

Name 
AAV-h-ATAD5-shRNA
Cat No 
shAAV-201610
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ATAD5.

shAAV-201610
AAV-h-ATAD5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ATAD5 (ATPase family, AAA domain containing 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ATPase family AAA domain-containing protein 5; C17orf41; chromosome fragility associated gene 1; chromosome fragility-associated gene 1 protein; ELG1; enhanced level of genomic instability 1 homolog; FRAG1
Description (eCommerce)
ATAD5/FRAG1 has been identified as a homolog of a subunit of RFC (replication factor C) and has been shown to be down-regulated in response to replicative stress. ATAD5/FRAG1 may play a role in the surveillance of DNA damage and the cell’s decision to survive or activate apoptosis.
Gene ID
79915
Gene Name (eCommerce)
ATPase family, AAA domain containing 5
Gene Name (Vector)
ATPase family, AAA domain containing 5
Gene Symbol
ATAD5
HGNC ID
HGNC:25752
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
5532
ORF Size (bp)
5532 bp
Protein Name (eCommerce)
ATPase family AAA domain-containing protein 5
RefSeq ID
NM_024857
RefSeq Synonyms
NM_024857, BC148343,
Research Areas
DNA Damage/Repair,Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,genetics,metabolism,transcription_translation
Species
human
Target Sentence
ATAD5/FRAG1 has been identified as a homolog of a subunit of RFC (replication factor C) and has been shown to be down-regulated in response to replicative stress. ATAD5/FRAG1 may play a role in the surveillance of DNA damage and the cell’s decision to survive or activate apoptosis.
UniGene ID
Hs.528902
UniProt ID (eCommerce)
Q96QE3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.