human ASNS shRNA silencing AAV

Name 
AAV-h-ASNS-shRNA
Cat No 
shAAV-201567
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ASNS.

shAAV-201567
AAV-h-ASNS-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ASNS (asparagine synthetase (glutamine-hydrolyzing)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ASNSD; asparagine synthetase glutamine-hydrolyzing; Cell cycle control protein TS11; glutamine-dependent asparagine synthetase; TS11; TS11 cell cycle control protein
Description (eCommerce)
Asparagine synthetase is involved in the synthesis of asparagine [taken from NCBI Entrez Gene (Gene ID: 440)].
Description (Vector)
ASNS is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene.
Gene ID
440
Gene Name (eCommerce)
asparagine synthetase (glutamine-hydrolyzing)
Gene Name (Vector)
asparagine synthetase (glutamine-hydrolyzing)
Gene Symbol
ASNS
HGNC ID
HGNC:753
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1686
ORF Size (bp)
1686 bp
Protein Name (eCommerce)
Asparagine synthetase [glutamine-hydrolyzing]
RefSeq ID
NM_001673
RefSeq Synonyms
NM_183356, NM_133436, NM_001673, NM_001178077, NM_001178076, NM_001178075, BC014621, BC008723,
Research Areas
Apoptosis,Cell Cycle,Gene Expression,Metabolism/Metabolic Process,Protein Folding
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,metabolism
Species
human
Target Sentence
Asparagine synthetase is involved in the synthesis of asparagine [taken from NCBI Entrez Gene (Gene ID: 440)].
UniGene ID
Hs.489207
UniProt ID (eCommerce)
P08243

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.