human ARIH2 shRNA silencing AAV

Name 
AAV-h-ARIH2-shRNA
Cat No 
shAAV-201388
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ARIH2.

shAAV-201388
AAV-h-ARIH2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ARIH2 (ariadne RBR E3 ubiquitin protein ligase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
all-trans retinoic acid inducible RING finger; ARI2; ARI-2; ariadne homolog 2; E3 ubiquitin-protein ligase ARIH2; protein ariadne-2 homolog; RING-type E3 ubiquitin transferase ARIH2; TRIAD1; Triad1 protein
Description (eCommerce)
Triad1 is an E3 ubiquitin-protein ligase mediating 'Lys-48'-and 'Lys-63'-linked polyubiquitination and subsequent proteasomal degradation of modified proteins. Triad1 may play a role in myelopoiesis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O95376].
Gene ID
10425
Gene Name (eCommerce)
ariadne RBR E3 ubiquitin protein ligase 2
Gene Name (Vector)
ariadne RBR E3 ubiquitin protein ligase 2
Gene Symbol
ARIH2
HGNC ID
HGNC:690
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1482
ORF Size (bp)
1482 bp
Protein Name (eCommerce)
E3 ubiquitin-protein ligase ARIH2
RefSeq ID
NM_006321
RefSeq Synonyms
NM_006321, NM_001317334, NM_001317333, BC000422,
Research Areas
Antigen Processing and Presentation,Immunology,Ubiquitination,Zinc-finger
Research Areas (Faceted)
cell_biology,immunology
Species
human
Target Sentence
Triad1 is an E3 ubiquitin-protein ligase mediating 'Lys-48'-and 'Lys-63'-linked polyubiquitination and subsequent proteasomal degradation of modified proteins. Triad1 may play a role in myelopoiesis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O95376].
UniGene ID
Hs.633601
UniProt ID (eCommerce)
O95376

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.