human ARID2 shRNA silencing AAV

Name 
AAV-h-ARID2-shRNA
Cat No 
shAAV-201378
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ARID2.

shAAV-201378
AAV-h-ARID2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ARID2 (AT-rich interaction domain 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ARID domain-containing protein 2; AT rich interactive domain 2 (ARID, RFX-like); AT-rich interactive domain-containing protein 2; BAF200; BRG1-associated factor 200; CSS6; p200; zinc finger protein with activation potential; zipzap/p200
Description (eCommerce)
The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. SWI/SNF complexes possess ATPase and DNA helicase activity that promotes transcriptional activation of genes normally repressed by chromatin structure. ARID2 (AT-rich interactive domain-containing protein 2) is also known as BAF200 and was purified as a factor that associated with PBAF (hSWI/SNF-B). ARID2 is a noncatalytic subunit that is a member of the ARID (AT-rich interactive domain-containing protein) family of DNA binding proteins. In addition to the ARID domain, ARID2 also contains a C2H2-type zinc finger and has been implicated as a transcriptional co-activator for serum response factor for the regulation of cardiac genes.
Description (Vector)
ARID2 is a subunit of the PBAF chromatin-remodeling complex (see BAF180; MIM 606083), which facilitates ligand-dependent transcriptional activation by nuclear receptors (Yan et al., 2005 (PubMed 15985610)).(supplied by OMIM, Mar 2008)
Gene ID
196528
Gene Name (eCommerce)
AT-rich interaction domain 2
Gene Name (Vector)
AT-rich interaction domain 2
Gene Symbol
ARID2
HGNC ID
HGNC:18037
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
5508
ORF Size (bp)
5508 bp
Protein Name (eCommerce)
AT-rich interactive domain-containing protein 2
RefSeq ID
NM_152641
RefSeq Synonyms
NM_152641, BC172461, BC156211,
Research Areas
Chromatin Remodeling,Immunology,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,transcription_translation,immunology,genetics
Species
human
Target Sentence
The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. SWI/SNF complexes possess ATPase and DNA helicase activity that promotes transcriptional activation of genes normally repressed by chromatin structure. ARID2 (AT-rich interactive domain-containing protein 2) is also known as BAF200 and was purified as a factor that associated with PBAF (hSWI/SNF-B). ARID2 is a noncatalytic subunit that is a member of the ARID (AT-rich interactive domain-containing protein) family of DNA binding proteins. In addition to the ARID domain, ARID2 also contains a C2H2-type zinc finger and has been implicated as a transcriptional co-activator for serum response factor for the regulation of cardiac genes.
UniGene ID
Hs.317304
UniProt ID (eCommerce)
Q68CP9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.