human AQR shRNA silencing AAV

Name
AAV-h-AQR-shRNA

Cat No
shAAV-201246

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human AQR.

shAAV-201246

AAV-h-AQR-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AQR (aquarius intron-binding spliceosomal factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

aquarius homolog; fSAP164; functional spliceosome-associated protein 164; IBP160; intron-binding protein aquarius; intron-binding protein of 160 kDa; RNA helicase aquarius

Description (eCommerce)

Intron-binding protein of 160 kDa (IBP160) is the human homolog of the mouse protein known as Aquarius. IBP160 is an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis.

Gene ID

9716

Gene Name (eCommerce)

aquarius intron-binding spliceosomal factor

Gene Name (Vector)

aquarius intron-binding spliceosomal factor

Gene Symbol

AQR

HGNC ID

HGNC:29513

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

4458

ORF Size (bp)

4458 bp

Protein Name (eCommerce)

Intron-binding protein aquarius

RefSeq ID

NM_014691

RefSeq Synonyms

NM_014691, BC127112, BC127111,

Research Areas

Gene Expression,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing,Spliceosome

Research Areas (Faceted)

genetics,transcription_translation,cell_biology

Species

human

Target Sentence

UniGene ID

Hs.510958

UniProt ID (eCommerce)

O60306

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.