human APOA5 shRNA silencing AAV

Name
AAV-h-APOA5-shRNA

Cat No
shAAV-201172

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human APOA5.

shAAV-201172

AAV-h-APOA5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human APOA5 (apolipoprotein A5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

APOAV; RAP3

Description (Vector)

APOA5 is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified.

Gene ID

116519

Gene Name (Vector)

apolipoprotein A5

Gene Symbol

APOA5

HGNC ID

HGNC:17288

ORF Size (aa)

1101

ORF Size (bp)

1101 bp

RefSeq ID

NM_052968

RefSeq Synonyms

NM_052968, NM_001166598, BC101789, BC101787,

Species

human

UniGene ID

Hs.283923

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.