human APLP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human APLP1.
shAAV-201158
AAV-h-APLP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human APLP1 (amyloid beta precursor like protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
APLP
Description (Vector)
APLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
333
Gene Name (Vector)
amyloid beta precursor like protein 1
Gene Symbol
APLP1
HGNC ID
HGNC:597
ORF Size (aa)
1953
ORF Size (bp)
1953 bp
RefSeq ID
NM_005166
RefSeq Synonyms
NM_005166, NM_001024807, BC012889,
Species
human
UniGene ID
Hs.74565
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.