human ANGPT4 shRNA silencing AAV

Name
AAV-h-ANGPT4-shRNA

Cat No
shAAV-200913

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ANGPT4.

shAAV-200913

AAV-h-ANGPT4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ANGPT4 (angiopoietin 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ANG3; ANG4

Description (Vector)

Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin.

Gene ID

51378

Gene Name (Vector)

angiopoietin 4

Gene Symbol

ANGPT4

HGNC ID

HGNC:487

ORF Size (aa)

1509

ORF Size (bp)

1509 bp

RefSeq ID

NM_015985

RefSeq Synonyms

NM_015985, NM_001322809, BC118495, BC111978, BC111976, BC111922,

Species

human

UniGene ID

Hs.278973

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.