human ANAPC13 shRNA silencing AAV

Name
AAV-h-ANAPC13-shRNA

Cat No
shAAV-200898

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ANAPC13.

shAAV-200898

AAV-h-ANAPC13-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ANAPC13 (anaphase promoting complex subunit 13). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

APC13; SWM1

Description (Vector)

ANAPC13 encodes a component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The encoded protein is evolutionarily conserved and is required for the integrity and ubiquitin ligase activity of the anaphase promoting complex. Pseudogenes and splice variants have been found for this gene; however, the biological validity of some of the splice variants has not been determined.

Gene ID

25847

Gene Name (Vector)

anaphase promoting complex subunit 13

Gene Symbol

ANAPC13

HGNC ID

HGNC:24540

ORF Size (aa)

225

ORF Size (bp)

225 bp

RefSeq ID

NM_015391

RefSeq Synonyms

NM_015391, NM_001242375, NM_001242374, BC005398,

Species

human

UniGene ID

Hs.106909

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.