human AMTN shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human AMTN.
shAAV-200876
AAV-h-AMTN-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human AMTN (amelotin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
UNQ689
Description (Vector)
The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (ENAM; MIM 606585), and ameloblastin (AMBN; MIM 601259), in the organic enamel matrix. Amelotin is specifically expressed in maturation-stage ameloblasts (Iwasaki et al., 2005 (PubMed 16304441)).(supplied by OMIM, Mar 2008)
Gene ID
401138
Gene Name (Vector)
amelotin
Gene Symbol
AMTN
HGNC ID
HGNC:33188
ORF Size (aa)
627
RefSeq ID
NM_212557
RefSeq Synonyms
NM_212557, NM_001286731, BC121817, BC121812,
Species
human
UniGene ID
Hs.453069
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.