human AMT shRNA silencing AAV

Name
AAV-h-AMT-shRNA

Cat No
shAAV-200874

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human AMT.

shAAV-200874

AAV-h-AMT-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AMT (aminomethyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

GCE; GCST; GCVT; NKH

Description (Vector)

AMT encodes one of four critical components of the glycine cleavage system. Mutations in this gene have been associated with glycine encephalopathy. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

275

Gene Name (Vector)

aminomethyltransferase

Gene Symbol

AMT

HGNC ID

HGNC:473

ORF Size (aa)

813

ORF Size (bp)

813 bp

RefSeq ID

NM_000481

RefSeq Synonyms

NM_001164712, NM_001164711, NM_001164710, NM_000481, BC044792, BC007546,

Species

human

UniGene ID

Hs.102

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.