human AMFR shRNA silencing AAV

Name 
AAV-h-AMFR-shRNA
Cat No 
shAAV-200844
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human AMFR.

shAAV-200844
AAV-h-AMFR-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AMFR (autocrine motility factor receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AMF receptor; Autocrine motility factor receptor; E3 ubiquitin-protein ligase AMFR; GP78; RING finger protein 45; RING-type E3 ubiquitin transferase AMFR; RNF45
Description (eCommerce)
gp78 is the specific receptor for autocrine motility factor. gp78 is also known as autocrine motility factor receptor, isoform 1(AMFR). Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells.
Description (Vector)
This locus encodes a glycosylated transmembrane receptor. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum-associated degradation of specific proteins.
Gene ID
267
Gene Name (eCommerce)
autocrine motility factor receptor
Gene Name (Vector)
autocrine motility factor receptor
Gene Symbol
AMFR
HGNC ID
HGNC:463
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1932
ORF Size (bp)
1932 bp
Protein Name (eCommerce)
E3 ubiquitin-protein ligase AMFR
RefSeq ID
NM_001144
RefSeq Synonyms
NM_001323512, NM_001323511, NM_001144, BC069197,
Research Areas
Aging,Neurobiology,Signal Transduction,Ubiquitination,Zinc-finger
Research Areas (Faceted)
cell_biology,neurobiology,signal_transduction
Species
human
Target Sentence
gp78 is the specific receptor for autocrine motility factor. gp78 is also known as autocrine motility factor receptor, isoform 1(AMFR). Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells.
UniGene ID
Hs.295137
UniProt ID (eCommerce)
Q9UKV5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.