human AMELX shRNA silencing AAV

Name
AAV-h-AMELX-shRNA

Cat No
shAAV-200839

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human AMELX.

shAAV-200839

AAV-h-AMELX-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AMELX (amelogenin, X-linked). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AI1E; AIH1; ALGN; AMG; AMGL; AMGX

Description (Vector)

AMELX encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in this gene cause X-linked amelogenesis imperfecta. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene ID

265

Gene Name (Vector)

amelogenin, X-linked

Gene Symbol

AMELX

HGNC ID

HGNC:461

ORF Size (aa)

576

ORF Size (bp)

576 bp

RefSeq ID

NM_001142

RefSeq Synonyms

NM_182681, NM_182680, NM_001142, BC074951, BC069118,

Species

human

UniGene ID

Hs.654436

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.