human ALKBH1 shRNA silencing AAV

Name 
AAV-h-ALKBH1-shRNA
Cat No 
shAAV-200785
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ALKBH1.

shAAV-200785
AAV-h-ALKBH1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ALKBH1 (alkB homolog 1, histone H2A dioxygenase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ABH; ABH1; alkB; ALKBH; hABH
Description (Vector)
ALKBH1 encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine.
Gene ID
8846
Gene Name (Vector)
alkB homolog 1, histone H2A dioxygenase
Gene Symbol
ALKBH1
HGNC ID
HGNC:17911
ORF Size (aa)
1170
ORF Size (bp)
1170 bp
RefSeq ID
NM_006020
RefSeq Synonyms
NM_006020, BC025787,
Species
human
UniGene ID
Hs.94542

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.